SCHEMBL1618931

SCHEMBL1618931

C=CC(C/C=C/C(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
GABRR1 P24046 2/20 0.44
GABRR2 P28476 2/20 0.44
BLM P54132 2/20 0.44
LMNA P02545 2/20 0.44
GABRR3 A8MPY1 1/20 0.44
APEX1 P27695 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TP53 P04637 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.33
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11372036 1.00 TSHR (0.44) TSHRGABRR1GABRR2BLMLMNA
Oxirane SCHEMBL10479243 0.91 GABRR1 (0.38) TSHRGABRR1GABRR2BLMLMNA
Phthalic Acid SCHEMBL6032841 0.83 ALDH1A1 (0.42) APEX1
SCHEMBL4043195 0.80 ACACB (0.30) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL10612739 0.79 GABRR1 (0.38) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL28149457 0.78 GRIK1 (0.44) TSHRBLMGRIK1GRIK2
SCHEMBL11086824 0.78 GRIK1 (0.31) GRIK1GRIK2
SCHEMBL11086820 0.78 GRIK1 (0.31) GRIK1GRIK2
SCHEMBL471837 0.77
SCHEMBL29953144 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107022326-A The IMD glue of roof panels high adhesion force 滁州金桥德克新材料有限公司 2017-08-08 CN claimed
US-5929196-A FOR USE IN THE PREPARATION OF SUSTAINED-RELEASE DRUGS SCHWARZ PHARMA AG (DE) 1999-07-27 US claimed
EP-0153104-B1 DIFFUSION COATED MULTIPLE-UNITS DOSAGE FORM BENZON PHARMA A/S (DK) 1993-04-21 EP claimed
EP-0153105-B1 DIFFUSION COATED MULTIPLE-UNITS DOSAGE FORM BENZON PHARMA A/S (DK) 1992-09-09 EP claimed
US-4716041-A SUSTAINED RELEASE A/S ALFRED BENZON (DK) 1987-12-29 US claimed
US-4713248-A MIXTURE OF FILM FORMING AGENT WITH COMPRESSIBLE POLYMER A/S ALFRED BENZON (DK) 1987-12-15 US claimed
EP-0153105-A2 Diffusion coated multiple-units dosage form BENZON PHARMA A/S (DK) 1985-08-28 EP claimed
EP-0153104-A2 Diffusion coated multiple-units dosage form BENZON PHARMA A/S (DK) 1985-08-28 EP claimed
WO-1985003437-A1 DIFFUSION COATED MULTIPLE-UNITS DOSAGE FORM A/S ALFRED BENZON (DK) 1985-08-15 WO claimed
WO-1985003436-A1 DIFFUSION COATED MULTIPLE-UNITS DOSAGE FORM A/S ALFRED BENZON (DK) 1985-08-15 WO claimed
EP-4314121-A1 COLOR MASTERBATCH FOR PRODUCING A COLORED PLASTIC ARTICLE AND METHOD FOR DECOLORING THE COLORED PLASTIC ARTICLE Smart Coloring GmbH (DE) 2024-02-07 EP disclosed
CN-108351445-A Thermochromic film and thermochromic composite 柯尼卡美能达株式会社 2018-07-31 CN disclosed
CN-107022326-A The IMD glue of roof panels high adhesion force 滁州金桥德克新材料有限公司 2017-08-08 CN disclosed
CN-103649790-B Optical reflection film and method for producing same 柯尼卡美能达株式会社 2016-10-19 CN disclosed
CN-103562756-B Infrared shielding film 柯尼卡美能达株式会社 2016-08-10 CN disclosed
US-4129644-A Protecting skin and hair with cosmetic compositions containing superoxide dismutase L'OREAL (FR) 1978-12-12 US disclosed
US-4065430-A Functional group containing polymer and method of preparing the same FUJI PHOTO FILM CO., LTD. (JA) 1977-12-27 US disclosed
US-3985499-A Diazamerocyanines for dyeing keratinous fibers L'OREAL (FR) 1976-10-12 US disclosed
US-3968310-A Half-ester reaction products of maleated alpha-olefins and monohydric alcohols A. E. STALEY MANUFACTURING COMPANY (US) 1976-07-06 US disclosed
US-3933885-A Cinnamylideneacetic acid esters FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed