Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1619357 | 0.96 | HRH3 (0.48) | HRH3KCNH2KDM4EALDH1A1AR | |
| SCHEMBL1619395 | 0.95 | HRH3 (0.45) | HRH3KCNH2KDM4EALDH1A1AR | |
| SCHEMBL1619052 | 0.92 | HRH3 (0.48) | HRH3KCNH2KDM4EALDH1A1AR | |
| SCHEMBL1619360 | 0.88 | KCNH2 (0.39) | HRH3KCNH2KDM4EALDH1A1POLB | |
| SCHEMBL1620192 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1POLBHTTBLM | |
| SCHEMBL1618885 | 0.86 | KCNH2 (0.41) | HRH3KCNH2KDM4EALDH1A1POLB | |
| SCHEMBL1619503 | 0.84 | HRH3 (0.44) | HRH3KCNH2KDM4EALDH1A1POLB | |
| SCHEMBL1619584 | 0.82 | KCNH2 (0.41) | HRH3KCNH2KDM4EALDH1A1POLB | |
| SCHEMBL3120178 | 0.82 | USP30 (0.45) | HRH3KCNH2ARUSP30SLC6A9 | |
| Trifluoroacetic Acid SCHEMBL3128408 | 0.82 | KCNH2 (0.42) | HRH3KCNH2KDM4EALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928225-B2 | Oxabispidine compounds for the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2011-04-19 | — | — | US | claimed |
| US-7928225-B2 | Oxabispidine compounds for the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2011-04-19 | — | — | US | disclosed |
| WO-2010138064-A1 | AQUEOUS FILM COATING COMPOSITION | ASTRAZENECA AB (SE) | 2010-12-02 | — | — | WO | disclosed |
| US-20100303920-A1 | Aqueous Film Coating Composition / 841 | ASTRAZENECA AB (SE) | 2010-12-02 | — | — | US | disclosed |
| WO-2010059119-A1 | A COMBINATION OF TERT -BUTYL (2-{7- [2- (4-CYANO-2- F LUOROPHENOXY) ETHYL] -9-OXA-3, 7-DIAZABICYCLO [3.3.1] NON-3- YL } ETHYL) CARBAMATE AND CERTAIN ANTIARRHYTHMIC BENZOFURANS | ASTRAZENECA AB (SE) | 2010-05-27 | — | — | WO | disclosed |
| WO-2009105023-A1 | PHARMACEUTICAL FORMULATION COMPRISING OXABISPIDINES / 236 | ASTRAZENECA AB (SE) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009105023-A1 | PHARMACEUTICAL FORMULATION COMPRISING OXABISPIDINES / 236 | ASTRAZENECA AB (SE) | 2009-08-27 | — | — | WO | disclosed |