SCHEMBL16192533

SCHEMBL16192533

CCCCNCC(C)[SiH](OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.34
ANPEP P15144 1/20 0.32
ERAP2 Q6P179 1/20 0.32
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ADH7 P40394 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL613651 0.76 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL4525517 0.74 TSHR (0.42) TSHRALDH1A1ANPEPERAP2ADH1B
SCHEMBL2089669 0.73 OPRM1 (0.37) ALDH1A1
SCHEMBL16192544 0.73
SCHEMBL444999 0.71
SCHEMBL18063240 0.71 OPRM1 (0.46) ADH1BADH1CADH1AADH7
SCHEMBL6327754 0.71 TSHR (0.30) TSHR
SCHEMBL27970484 0.71
SCHEMBL28992780 0.70 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL28992777 0.70 ALDH1A1 (0.32) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220220247-A1 Composition Comprising Silylated Polymer HUNTSMAN INTERNATIONAL LLC 2022-07-14 US disclosed
EP-2989155-B1 COMPOSITION COMPRISING SILYLATED POLYMERS HUNTSMAN INT LLC (US) 2018-10-03 EP disclosed
US-9752013-B2 Composition comprising silylated polymers HUNTSMAN INTERNATIONAL LLC (US) 2017-09-05 US disclosed
EP-2989155-A1 COMPOSITION COMPRISING SILYLATED POLYMERS Huntsman International LLC (US) 2016-03-02 EP disclosed
US-20160046793-A1 Composition Comprising Silylated Polymers HUNTSMAN INTERNATIONAL LLC 2016-02-18 US disclosed
WO-2014173638-A1 COMPOSITION COMPRISING SILYLATED POLYMERS HUNTSMAN INTERNATIONAL LLC (US) 2014-10-30 WO disclosed
EP-2796493-A1 Composition comprising silylated polymers and polyhedral oligomeric metallo silsesquioxane HUNTSMAN INTERNATIONAL LLC (US) 2014-10-29 EP disclosed