Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16193348 | 0.89 | BCHE (0.35) | LGALS8ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL16156885 | 0.88 | LTA4H (0.35) | LGALS8ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL14905962 | 0.88 | LTA4H (0.35) | LGALS8ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL16193346 | 0.86 | LGALS8 (0.35) | LGALS8ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL14905964 | 0.86 | LGALS8 (0.35) | LGALS8ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL16193354 | 0.85 | LGALS8 (0.37) | LGALS8ALDH1A1BCHECCR6PAX8 | |
| SCHEMBL16156827 | 0.84 | LGALS8 (0.40) | LGALS8ALDH1A1BCHE | |
| SCHEMBL16156837 | 0.82 | LGALS8 (0.30) | LGALS8 | |
| SCHEMBL14905934 | 0.81 | LGALS8 (0.33) | LGALS8ALDH1A1BCHE | |
| SCHEMBL16156791 | 0.81 | LGALS8 (0.33) | LGALS8ALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070464-A1 | COFACTOR ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-04-27 | — | — | WO | disclosed |
| WO-2014172330-A1 | METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2014-10-23 | — | — | WO | disclosed |