Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14823540 | 0.91 | MAPT (0.62) | MAPTALDH1A1THRBRECQLHSD17B10 | |
| SCHEMBL611721 | 0.83 | MAPT (0.53) | MAPTALDH1A1THRBRECQLHSD17B10 | |
| SCHEMBL3191322 | 0.80 | HSD17B10 (0.59) | MAPTALDH1A1THRBRECQLHSD17B10 | |
| SCHEMBL1105741 | 0.80 | ALDH1A1 (0.49) | MAPTALDH1A1THRBRECQLHSD17B10 | |
| SCHEMBL16195477 | 0.80 | MAPT (0.60) | MAPTALDH1A1THRBRECQLHSD17B10 | |
| Water SCHEMBL1044054 | 0.79 | HSD17B10 (0.58) | MAPTALDH1A1THRBRECQLHSD17B10 | |
| SCHEMBL16195792 | 0.78 | CYP2C19 (0.51) | MAPTALDH1A1THRBRECQLHSD17B10 | |
| SCHEMBL6556048 | 0.76 | HSD17B10 (0.58) | MAPTALDH1A1THRBRECQLHSD17B10 | |
| SCHEMBL10747902 | 0.76 | HSD17B10 (0.61) | MAPTALDH1A1THRBRECQLHSD17B10 | |
| SCHEMBL9226505 | 0.76 | MAPT (0.62) | MAPTALDH1A1THRBRECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738786-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2017-08-22 | — | — | US | disclosed |
| EP-2758475-B1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LTD (GB) | 2017-04-26 | — | — | EP | disclosed |
| US-20160355683-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-12-08 | — | — | US | disclosed |
| US-9376568-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-06-28 | — | — | US | disclosed |
| US-20150274976-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-10-01 | — | — | US | disclosed |
| US-9085698-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-07-21 | — | — | US | disclosed |
| US-20140323741-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LTD. (GB) | 2014-10-30 | — | — | US | disclosed |