Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPP5C | P53041 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15001080 | 1.00 | L3MBTL1 (0.35) | L3MBTL1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL21938530 | 1.00 | L3MBTL1 (0.35) | L3MBTL1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL22906311 | 1.00 | L3MBTL1 (0.35) | L3MBTL1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL15001079 | 0.87 | L3MBTL1 (0.34) | L3MBTL1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL15001081 | 0.84 | L3MBTL1 (0.35) | L3MBTL1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL2122883 | 0.82 | L3MBTL1 (0.40) | L3MBTL1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL516059 | 0.79 | L3MBTL1 (0.38) | L3MBTL1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL16196649 | 0.79 | L3MBTL1 (0.38) | L3MBTL1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL15839601 | 0.78 | CNR1 (0.32) | — | |
| SCHEMBL16271862 | 0.77 | TLR9 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785181-B1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2016-08-17 | — | — | EP | disclosed |
| US-9107415-B2 | 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds, and derivatives thereof | SYNGENTA PARTICPATIONS AG (CH) | 2015-08-18 | — | — | US | disclosed |
| US-20140323303-A1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323303-A1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | CNPY2, CBR3, CBR1 | L3MBTL1 965/4885KDM4E 280/4885GMNN 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.