Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16196868 | 0.81 | PPARA (0.32) | PPARDPPARA | |
| SCHEMBL16196770 | 0.80 | PPARA (0.34) | PPARDPPARA | |
| SCHEMBL16196955 | 0.78 | PPARA (0.34) | PPARDPPARA | |
| SCHEMBL16197181 | 0.78 | PPARA (0.33) | PPARDPPARA | |
| SCHEMBL16196995 | 0.75 | PPARA (0.35) | PPARDPPARA | |
| SCHEMBL16196852 | 0.75 | PPARA (0.32) | PPARDPPARA | |
| Bromide SCHEMBL18112607 | 0.74 | — | — | |
| SCHEMBL16013778 | 0.74 | — | — | |
| SCHEMBL16013858 | 0.74 | MAPT (0.31) | — | |
| SCHEMBL16013802 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014172871-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | WO | disclosed |