Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16196770 | 0.85 | PPARA (0.34) | PPARAPPARD | |
| SCHEMBL16196868 | 0.83 | PPARA (0.32) | PPARAPPARD | |
| SCHEMBL16196955 | 0.83 | PPARA (0.34) | PPARAPPARDPPARG | |
| SCHEMBL16197181 | 0.83 | PPARA (0.33) | PPARAPPARD | |
| SCHEMBL16197179 | 0.83 | NPC1 (0.35) | PPARAPPARDKDM4EMAPT | |
| SCHEMBL16196851 | 0.80 | ATM (0.40) | PPARAPPARDALDH1A1KDM4ELMNA | |
| SCHEMBL16196852 | 0.80 | PPARA (0.32) | PPARAPPARD | |
| SCHEMBL16196791 | 0.78 | AKR1C3 (0.33) | PPARAPPARD | |
| SCHEMBL16196790 | 0.78 | AKR1C3 (0.33) | PPARAPPARD | |
| SCHEMBL16196832 | 0.78 | ACHE (0.32) | PPARAPPARDALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014172871-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | WO | disclosed |