Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16196832 | 0.88 | ACHE (0.32) | MAPTPOLBPPARAPPARD | |
| SCHEMBL16196851 | 0.87 | ATM (0.40) | MAPTKDM4EPPARAPPARD | |
| SCHEMBL16196768 | 0.87 | PDK2 (0.37) | MAPTKDM4EPDK2 | |
| SCHEMBL16197174 | 0.87 | NR4A1 (0.39) | PPARAPPARD | |
| SCHEMBL16197176 | 0.87 | NR4A1 (0.39) | PPARAPPARD | |
| SCHEMBL16196754 | 0.83 | PPARD (0.31) | PPARAPPARD | |
| SCHEMBL16196753 | 0.83 | PPARD (0.31) | PPARAPPARD | |
| SCHEMBL16196755 | 0.83 | PPARD (0.31) | PPARAPPARD | |
| SCHEMBL16196937 | 0.83 | MAPT (0.43) | NPC1MAPTRAB9AKDM4EPOLB | |
| SCHEMBL16196995 | 0.83 | PPARA (0.35) | MAPTKDM4EPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014172871-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | WO | disclosed |
| WO-2014172871-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | WO | disclosed |