Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14909757 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL28608405 | 0.77 | CA2 (0.31) | CA2MAPK1 | |
| SCHEMBL14909281 | 0.77 | TSHR (0.30) | TSHR | |
| SCHEMBL14910256 | 0.77 | TSHR (0.30) | TSHR | |
| SCHEMBL1643940 | 0.74 | — | — | |
| SCHEMBL1642847 | 0.74 | — | — | |
| SCHEMBL14910414 | 0.74 | — | — | |
| SCHEMBL14909153 | 0.74 | — | — | |
| SCHEMBL14910434 | 0.74 | LMNA (0.35) | CA2MAPK1 | |
| SCHEMBL19138932 | 0.73 | TP53 (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2989082-A1 | NOVEL SYNTHETIC PROCESS TO 8-CHLORO-1-METHYL-BENZO[D]AZEPINE, NOVEL INTERMEDIATES AND THE PRODUCTION THEREOF | LEK Pharmaceuticals d.d. (SI) | 2016-03-02 | — | — | EP | disclosed |
| WO-2014173928-A1 | NOVEL SYNTHETIC PROCESS TO 8-CHLORO-1-METHYL-BENZO[D]AZEPINE, NOVEL INTERMEDIATES AND THE PRODUCTION THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2014-10-30 | — | — | WO | disclosed |