Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197620 | 0.84 | KMT2A (0.75) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL16197384 | 0.83 | LMNA (0.74) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL16197406 | 0.82 | SMN1; SMN2 (0.73) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL16197394 | 0.81 | LMNA (0.60) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL16197089 | 0.81 | LMNA (0.72) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL16197436 | 0.80 | LMNA (0.58) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL28020621 | 0.80 | KMT2A (0.73) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL22441396 | 0.79 | SMN1; SMN2 (0.68) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2916275 | 0.79 | SMN1; SMN2 (0.79) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| Bicarbonate SCHEMBL15225914 | 0.77 | SMN1; SMN2 (0.70) | LMNAMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014173904-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY | VIB VZW (BE) | 2014-10-30 | — | — | WO | disclosed |