Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | STK25 | O00506 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197436 | 0.99 | LMNA (0.58) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16197443 | 0.81 | LMNA (0.71) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16208828 | 0.76 | TDP1 (0.69) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL16197384 | 0.76 | LMNA (0.74) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16197460 | 0.75 | TDP1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL16197089 | 0.74 | LMNA (0.72) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16197620 | 0.74 | KMT2A (0.75) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL12169393 | 0.74 | SMN1; SMN2 (0.71) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20389337 | 0.73 | HDAC8 (0.48) | ALDH1A1GAAHPGD | |
| SCHEMBL28020621 | 0.73 | KMT2A (0.73) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014173904-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY | VIB VZW (BE) | 2014-10-30 | — | — | WO | disclosed |
| WO-2014173904-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY | VIB VZW (BE) | 2014-10-30 | — | — | WO | disclosed |