Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15425743 | 0.81 | CYP19A1 (0.67) | HSP90AB1CYP19A1MAOAMAOB | |
| SCHEMBL18377684 | 0.81 | HDAC1 (0.50) | HDAC1CYP19A1SMN1; SMN2NR1I3 | |
| SCHEMBL3107176 | 0.80 | HDAC1 (0.50) | HDAC1CYP19A1MAPTSMN1; SMN2NR1I3 | |
| SCHEMBL29894985 | 0.79 | TDP1 (0.63) | MAPTSMN1; SMN2LIN28ATDP1MAOA | |
| SCHEMBL210394 | 0.79 | TDP1 (0.63) | MAPTSMN1; SMN2LIN28ATDP1MAOA | |
| SCHEMBL18028297 | 0.78 | HSP90AB1 (0.70) | HSP90AB1CYP19A1 | |
| SCHEMBL18367612 | 0.77 | HDAC1 (0.47) | HDAC1CYP19A1SMN1; SMN2NR1I3 | |
| SCHEMBL30574694 | 0.76 | L3MBTL1 (0.57) | HDAC1CYP19A1MAPTSMN1; SMN2NR1I3 | |
| SCHEMBL15425744 | 0.75 | CYP19A1 (0.64) | HDAC1CYP19A1NR1I3 | |
| SCHEMBL16620124 | 0.74 | HSP90AB1 (0.61) | HDAC1HSP90AB1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871940-B2 | Unsymmetrical bisazides for chemoselective sequential ligation | The Florida State University Research Foundation, Inc. (US) | 2014-10-28 | — | — | US | disclosed |
| US-8871940-B2 | Unsymmetrical bisazides for chemoselective sequential ligation | The Florida State University Research Foundation, Inc. (US) | 2014-10-28 | — | — | US | disclosed |