Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.63 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29894985 | 1.00 | TDP1 (0.63) | TDP1MAPTSMN1; SMN2LIN28AKCNA5 | |
| Acetaldehyde SCHEMBL27331159 | 0.90 | SMN1; SMN2 (0.53) | TDP1MAPTSMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL804182 | 0.86 | TDP1 (0.63) | TDP1MAPTSMN1; SMN2LIN28AKCNA5 | |
| Hydrochloric Acid SCHEMBL28308406 | 0.84 | TDP1 (0.61) | TDP1MAPTSMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL30191149 | 0.84 | SMN1; SMN2 (0.79) | TDP1MAPTSMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL22928656 | 0.83 | TDP1 (0.59) | TDP1MAPTSMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL996544 | 0.83 | TDP1 (0.64) | TDP1MAPTSMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL12888692 | 0.83 | TDP1 (0.59) | TDP1MAPTSMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL3459116 | 0.83 | TDP1 (0.59) | TDP1MAPTSMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL12633560 | 0.83 | TDP1 (0.59) | TDP1MAPTSMN1; SMN2LIN28AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117026295-A | COF composite material and preparation method and application thereof | 深圳技术大学 | 2023-11-10 | — | — | CN | claimed |
| CN-113200937-B | Method for preparing 1,2-benzisothiazolin-3-one by catalytic oxidation | 郑州大学 | 2022-12-13 | — | — | CN | claimed |
| CN-109148796-B | Acid scavenging functional diaphragm for lithium ion electrochemical cell functional performance | 通用汽车环球科技运作有限责任公司 | 2022-01-25 | — | — | CN | claimed |
| CN-113200937-A | Method for preparing 1, 2-benzisothiazolin-3-one by catalytic oxidation | 郑州大学 | 2021-08-03 | — | — | CN | claimed |
| CN-109148796-A | Acid for lithium ion electrochemical cells power-performance removes function diaphragm | 通用汽车环球科技运作有限责任公司 | 2019-01-04 | — | — | CN | claimed |
| US-20140171431-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2014-06-19 | — | — | US | claimed |
| EP-2725024-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2014-04-30 | — | — | EP | claimed |
| US-8182718-B2 | Ligand exchange thermochromic systems and high ε ligands for same | PLEOTINT, L.L.C. (US) | 2012-05-22 | — | — | US | claimed |
| EP-1023271-A4 | PROCESS FOR THE SYNTHESIS OF CARBAPENEM INTERMEDIATES, AND COMPOUNDS PRODUCED | MERCK & CO INC (US) | 2001-09-12 | — | — | EP | claimed |
| EP-1023271-A1 | PROCESS FOR THE SYNTHESIS OF CARBAPENEM INTERMEDIATES, AND COMPOUNDS PRODUCED | Merck & Co., Inc. (US) | 2000-08-02 | — | — | EP | claimed |
| WO-1999018078-A1 | PROCESS FOR THE SYNTHESIS OF CARBAPENEM INTERMEDIATES, AND COMPOUNDS PRODUCED | MERCK & CO., INC. (US) | 1999-04-15 | — | — | WO | claimed |
| JP-56127393-A | — | — | None | — | — | JP | disclosed |
| US-12545805-B2 | Manganese-bearing polymer complexes | UMICORE (BE) | 2026-02-10 | — | — | US | disclosed |
| CN-117026295-A | COF composite material and preparation method and application thereof | 深圳技术大学 | 2023-11-10 | — | — | CN | disclosed |
| EP-3860561-B1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS INC (US) | 2023-06-21 | — | — | EP | disclosed |
| EP-0457386-A2 | Process for the preparation of a secondary amine and catalysts therefor | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-11-21 | — | — | EP | disclosed |
| EP-0156191-B1 | CONDENSED DIAZEPINONES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1989-07-19 | — | — | EP | disclosed |
| US-4550107-A | Condensed diazepinones, their compositions and methods of use as pharmaceuticals | DR. KARL THOMAE GMBH (DE) | 1985-10-29 | — | — | US | disclosed |
| EP-0156191-A2 | Condensed diazepinones, process for their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-10-02 | — | — | EP | disclosed |
| JP-S56127393-A | ANTIBACTERIAL AGENT | BRISTOL MAYERS KENKYUSHO KK | 1981-10-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171431-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | PLA2G5, LTA4H, PLA2G4A | TDP1 2764/4885MAPT 4529/4885SMN1; SMN2 3347/4885 |
| US-12545805-B2 | Manganese-bearing polymer complexes | PUF60, DPY30, RPLP0 | TDP1 1211/4885MAPT 40/4885SMN1; SMN2 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.