Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537017 | 0.91 | KDM4E (0.47) | MAPTALOX12MAPK1MEN1KMT2A | |
| SCHEMBL16199485 | 0.79 | MAP3K11 (0.50) | MAPTALOX12MAPK1MEN1KMT2A | |
| SCHEMBL12233436 | 0.75 | MEN1 (0.38) | MAPTALOX12MAPK1MEN1KMT2A | |
| SCHEMBL12233267 | 0.75 | ALDH1A1 (0.44) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL4637336 | 0.74 | ADORA2A (0.60) | ADORA2A | |
| SCHEMBL8190562 | 0.74 | ALDH1A1 (0.67) | MAPTALOX12MAPK1MEN1KMT2A | |
| SCHEMBL12233273 | 0.72 | ALDH1A1 (0.40) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL12233269 | 0.71 | ALDH1A1 (0.45) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL4637377 | 0.70 | HPGD (0.40) | MAPTALOX12MAPK1MEN1KMT2A | |
| SCHEMBL2536378 | 0.70 | ADORA2A (0.41) | MAPTMEN1KMT2ARXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097415-B1 | 8-ETHINYLXANTHINE DERIVATIVES AS SELECTIVE A2A RECEPTOR ANTAGONISTS | UNIV BONN (DE) | 2014-10-29 | — | — | EP | disclosed |