Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190111 | 0.72 | PTGES (0.42) | MAPTKDM4EKMT2AHPGDMEN1 | |
| SCHEMBL16199740 | 0.71 | NR2E3 (0.37) | MAPTKDM4EKMT2AHPGDMEN1 | |
| SCHEMBL9899450 | 0.70 | MAP2K7 (0.41) | MAPTSMN1; SMN2HTT | |
| SCHEMBL13190105 | 0.69 | PTGES (0.40) | MAPTKDM4EKMT2AHPGDMEN1 | |
| SCHEMBL13190114 | 0.69 | PTGES (0.39) | MAPTKDM4EKMT2AHPGDMEN1 | |
| SCHEMBL1968399 | 0.68 | POLB (0.58) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL13190116 | 0.68 | MAPT (0.39) | MAPTKDM4EKMT2AHPGDMEN1 | |
| SCHEMBL11962208 | 0.68 | PTGES (0.41) | MAPTKDM4EKMT2AHPGDMEN1 | |
| SCHEMBL1725936 | 0.68 | CYP4F2 (0.42) | MAPTKMT2AHPGDTDP1HDAC11 | |
| SCHEMBL13189730 | 0.68 | PTGES (0.38) | MAPTKDM4EKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-B1 | 2-AMINOBENZIMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-29 | — | — | EP | disclosed |