Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 14/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1690247 | 0.79 | PTGDR2 (0.58) | — | |
| SCHEMBL27658715 | 0.76 | IDO1 (0.43) | CNR2 | |
| SCHEMBL4778926 | 0.69 | ACLY (0.58) | FFAR4FFAR1 | |
| SCHEMBL1690287 | 0.68 | PTGDR2 (0.56) | CNR2 | |
| Hydrochloric Acid SCHEMBL9083841 | 0.68 | ACLY (0.57) | FFAR4FFAR1 | |
| SCHEMBL5440013 | 0.67 | FFAR4 (0.66) | FFAR4FFAR1 | |
| SCHEMBL6207183 | 0.66 | ACLY (0.63) | — | |
| SCHEMBL13606217 | 0.66 | CNR2 (0.51) | CNR2 | |
| SCHEMBL10276916 | 0.65 | ACLY (0.65) | — | |
| SCHEMBL10896486 | 0.64 | STK4 (0.44) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611091-B1 | Substituted phenylalkanoic acid derivatives and their use for respiratory disease treatment | ASTRAZENECA AB (SE) | 2014-10-29 | — | — | EP | disclosed |