Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 16/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13089762 | 0.85 | MET (0.56) | METKMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1302898 | 0.79 | MET (0.60) | METKMT2AMEN1IRAK4 | |
| SCHEMBL13089760 | 0.78 | MET (0.61) | METKMT2AMEN1 | |
| SCHEMBL4130448 | 0.77 | MET (0.69) | METKMT2AALDH1A1MEN1 | |
| SCHEMBL13089759 | 0.77 | MET (0.68) | METKMT2AMEN1 | |
| SCHEMBL1950688 | 0.77 | MET (0.71) | METKMT2AMEN1IRAK4 | |
| SCHEMBL13089799 | 0.77 | MET (0.66) | METIRAK4 | |
| Acetic Acid SCHEMBL3046972 | 0.76 | MET (0.60) | METKMT2AMEN1 | |
| SCHEMBL1302552 | 0.76 | MET (0.64) | METKMT2AMEN1 | |
| SCHEMBL3062465 | 0.76 | MET (0.64) | METIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164843-B1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2014-10-29 | — | — | EP | disclosed |