Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212200 | 0.79 | ENPP1 (0.47) | KDM4EALOX12SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL16199847 | 0.77 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2ALDH1A1GLAGAA | |
| SCHEMBL12569041 | 0.73 | EGFR (0.46) | KDM4EALOX12SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL13090425 | 0.72 | SLC2A1 (0.50) | KDM4EALOX12SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL13438277 | 0.69 | EGFR (0.42) | KDM4EALOX12SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL1999978 | 0.68 | ENPP1 (0.54) | KDM4EALOX12SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL15867097 | 0.68 | ACHE (0.57) | KDM4EALOX12SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL13059865 | 0.65 | ENPP1 (0.47) | KDM4EALOX12ALDH1A1MAPTHPGD | |
| SCHEMBL217338 | 0.65 | PDE10A (0.52) | EGFRACHEPDE10ABACE1ENPP1 | |
| SCHEMBL6064319 | 0.65 | ACHE (0.53) | KDM4EALOX12SMN1; SMN2ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190287-B1 | TARTRATE SALTS OR COMPLEXES OF QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS INC (US) | 2014-10-29 | — | — | EP | disclosed |