Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14044199 | 0.82 | GABRB3 (0.34) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL14039851 | 0.80 | CYP2C9 (0.38) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL17468326 | 0.77 | RAB9A (0.40) | — | |
| SCHEMBL14039840 | 0.76 | MEN1 (0.31) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL13683111 | 0.76 | OPRL1 (0.34) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL14201637 | 0.73 | KMT2A (0.36) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL14039838 | 0.71 | — | — | |
| SCHEMBL13693058 | 0.70 | ADORA2A (0.39) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL13066536 | 0.70 | KDM4E (0.38) | NOTUMMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16200400 | 0.69 | KDM4E (0.36) | NOTUMMEN1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720545-B1 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX INC (US) | 2014-10-29 | — | — | EP | disclosed |