Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17545763 | 0.84 | KMT2A (0.44) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL12574599 | 0.80 | ALDH1A1 (0.36) | ALDH1A1HPGDFFAR1KCNH2PSEN1 | |
| SCHEMBL17540354 | 0.77 | CTRC (0.45) | KCNH2AKR1C2 | |
| SCHEMBL11331364 | 0.74 | MEN1 (0.43) | MEN1KMT2AALDH1A1TDP1NPC1 | |
| SCHEMBL1045006 | 0.74 | AHR (0.57) | — | |
| SCHEMBL13494486 | 0.74 | NOTUM (0.44) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL4058252 | 0.73 | SLC6A4 (0.45) | HPGDNPC1RAB9AHTR2ASLC6A4 | |
| SCHEMBL27395925 | 0.72 | NOTUM (0.43) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL28533539 | 0.71 | DHODH (0.50) | MEN1KMT2AALDH1A1HPGDFFAR1 | |
| SCHEMBL16618296 | 0.71 | TP53 (0.47) | MEN1KMT2AALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507341-B1 | COMPONENTS FOR HIGH FREQUENCY TECHNOLOGY, LIQUID CRYSTAL MEDIA AND COMPOUNDS | MERCK PATENT GMBH (DE) | 2014-10-29 | — | — | EP | disclosed |