Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11981917 | 1.00 | SLC7A5 (0.50) | SLC7A5ANPEPENPEPEPHX1MAOB | |
| SCHEMBL14640313 | 0.86 | ANPEP (0.63) | SLC7A5ANPEPENPEPFOLH1 | |
| SCHEMBL1043826 | 0.83 | ANPEP (0.55) | SLC7A5ANPEPENPEPEPHX1 | |
| SCHEMBL6105481 | 0.83 | ANPEP (0.55) | SLC7A5ANPEPENPEPEPHX1 | |
| SCHEMBL9663627 | 0.82 | SLC7A5 (0.49) | SLC7A5ANPEPENPEPGRIA2NOS3 | |
| SCHEMBL7176658 | 0.81 | PRSS1 (0.56) | — | |
| SCHEMBL7176662 | 0.81 | PRSS1 (0.56) | — | |
| SCHEMBL455835 | 0.81 | SLC7A5 (0.73) | SLC7A5ANPEPENPEPGRIA2NOS3 | |
| SCHEMBL37182814 | 0.81 | SLC7A5 (0.73) | SLC7A5ANPEPENPEPGRIA2NOS3 | |
| SCHEMBL455836 | 0.81 | SLC7A5 (0.73) | SLC7A5ANPEPENPEPGRIA2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2796546-A1 | In vivo incorporation of unnatural amino acids | The Scripps Research Institute (US) | 2014-10-29 | — | — | EP | disclosed |