Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 8/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | ALPI | P09923 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | XIAP | P98170 | 1/20 | 0.62 |
| ▸ | NOS3 | P29474 | 3/20 | 0.61 |
| ▸ | NOS1 | P29475 | 3/20 | 0.61 |
| ▸ | NOS2 | P35228 | 3/20 | 0.61 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.59 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26008172 | 1.00 | SLC7A5 (0.73) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL37182814 | 1.00 | SLC7A5 (0.73) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL455836 | 1.00 | SLC7A5 (0.73) | SLC7A5PTGS1ALPIPKMXIAP | |
| Hydrochloric Acid SCHEMBL30655752 | 0.98 | SLC7A5 (0.71) | SLC7A5PTGS1ALPIPKMXIAP | |
| Hydrochloric Acid SCHEMBL598770 | 0.98 | SLC7A5 (0.71) | SLC7A5PTGS1ALPIPKMXIAP | |
| Hydrochloric Acid SCHEMBL598769 | 0.98 | SLC7A5 (0.71) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL321517 | 0.88 | SLC7A5 (0.70) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL29430350 | 0.88 | SLC7A5 (0.70) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL1061213 | 0.88 | SLC7A5 (0.70) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL1061212 | 0.88 | SLC7A5 (0.70) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250325632-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES | Synthorx, Inc. (US) | 2025-10-23 | — | — | US | claimed |
| US-20250325633-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | Synthorx, Inc. (US) | 2025-10-23 | — | — | US | claimed |
| US-12377131-B2 | Cytokine conjugates for the treatment of autoimmune diseases | Synthorx, Inc. (US) | 2025-08-05 | — | — | US | claimed |
| US-12318431-B2 | Cytokine conjugates for the treatment of proliferative and infectious diseases | Synthorx, Inc. (US) | 2025-06-03 | — | — | US | claimed |
| EP-4539887-A1 | INTERLEUKIN-2 PRODRUGS | Merck Sharp & Dohme LLC (US) | 2025-04-23 | — | — | EP | claimed |
| US-20240287151-A1 | IL-15 Conjugates and Uses Thereof | Synthorx, Inc. (US) | 2024-08-29 | — | — | US | claimed |
| US-20240101631-A1 | HUMAN INTERLEUKIN-2 CONJUGATES BIASED FOR THE INTERLEUKIN-2 RECEPTOR BETA-GAMMAC DIMER AND CONJUGATED TO A NONPEPTIDIC, WATER-SOLUBLE POLYMER | MERCK SHARP & DOHME LLC (US) | 2024-03-28 | — | — | US | claimed |
| US-20240082359-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES | Synthorx, Inc. (US) | 2024-03-14 | — | — | US | claimed |
| US-11919934-B2 | IL-15 conjugates and uses thereof | Synthorx, Inc. (US) | 2024-03-05 | — | — | US | claimed |
| WO-2023244517-A1 | INTERLEUKIN-2 PRODRUGS | MERCK SHARP & DOHME LLC (US) | 2023-12-21 | — | — | WO | claimed |
| US-9644014-B2 | Modified animal erythropoietin polypeptides and their uses | AMBRX, INC. (US) | 2017-05-09 | — | — | US | claimed |
| EP-2665744-B1 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | UNIV ROCHESTER (US) | 2015-04-08 | — | — | EP | claimed |
| EP-2062976-A2 | Site specific incorporation of keto amino acids into proteins | The Scripps Research Institute (US) | 2009-05-27 | — | — | EP | claimed |
| EP-1945262-A2 | FC LABELING FOR IMMUNOSTAINING AND IMMUNOTARGETING | The Scripps Research Institute (US) | 2008-07-23 | — | — | EP | claimed |
| WO-2007048127-A9 | FC LABELING FOR IMMUNOSTAINING AND IMMUNOTARGETING | SCRIPPS RESEARCH INST (US) | 2007-06-07 | — | — | WO | claimed |
| US-20070122408-A1 | Fc Labeling for Immunostaining and Immunotargeting | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-05-31 | — | — | US | claimed |
| WO-2007048127-A2 | FC LABELING FOR IMMUNOSTAINING AND IMMUNOTARGETING | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-04-26 | — | — | WO | claimed |
| EP-1490483-A2 | IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | The Scripps Research Institute (US) | 2004-12-29 | — | — | EP | claimed |
| US-20030082575-A1 | Translation system for use in the generation of protein containing adjusted amino acid sequences | THE SCRIPPS RESEARCH INSTITUTE (US) | 2003-05-01 | — | — | US | claimed |
| WO-2002085923-A2 | IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-10-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287151-A1 | IL-15 Conjugates and Uses Thereof | IL15, IL15RA, IL2 | SLC7A5 757/4885PTGS1 895/4885ALPI 1117/4885 |
| US-20250325633-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | IL2, IL2RA, IL15 | SLC7A5 2484/4885PTGS1 1447/4885ALPI 1243/4885 |
| US-12318431-B2 | Cytokine conjugates for the treatment of proliferative and infectious diseases | IL2, IL2RA, IL36G | SLC7A5 1836/4885PTGS1 1611/4885ALPI 506/4885 |
| US-20240101631-A1 | HUMAN INTERLEUKIN-2 CONJUGATES BIASED FOR THE INTERLEUKIN-2 RECEPTOR BETA-GAMMAC DIMER AND CONJUGATED TO A NONPEPTIDIC, WATER-SOLUBLE POLYMER | IL2, IL2RA, IL6ST | SLC7A5 835/4885PTGS1 1583/4885ALPI 3762/4885 |
| US-20240082359-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES | IL2, IL2RA, IL36G | SLC7A5 1836/4885PTGS1 1611/4885ALPI 506/4885 |
| US-20250325632-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES | IL2, IL2RA, IL36G | SLC7A5 1836/4885PTGS1 1611/4885ALPI 506/4885 |
| US-20070122408-A1 | Fc Labeling for Immunostaining and Immunotargeting | FCGR3B, FCGR2A, FCGR1A | SLC7A5 4055/4885PTGS1 4364/4885ALPI 1694/4885 |
| US-12377131-B2 | Cytokine conjugates for the treatment of autoimmune diseases | IL2, IL2RA, IL15 | SLC7A5 2484/4885PTGS1 1447/4885ALPI 1243/4885 |
| US-11919934-B2 | IL-15 conjugates and uses thereof | IL15, IL15RA, IL2 | SLC7A5 757/4885PTGS1 895/4885ALPI 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.