Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.55 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.55 |
| ▸ | PNMT | P11086 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043826 | 1.00 | ANPEP (0.55) | ANPEPENPEPSLC7A5PNMTTAAR1 | |
| SCHEMBL29478099 | 0.87 | SLC7A5 (0.49) | ANPEPENPEPSLC7A5EPHX1 | |
| SCHEMBL4054915 | 0.87 | SLC7A5 (0.49) | ANPEPENPEPSLC7A5EPHX1 | |
| SCHEMBL455835 | 0.86 | SLC7A5 (0.73) | ANPEPENPEPSLC7A5HTR2A | |
| SCHEMBL455836 | 0.86 | SLC7A5 (0.73) | ANPEPENPEPSLC7A5HTR2A | |
| SCHEMBL26008172 | 0.86 | SLC7A5 (0.73) | ANPEPENPEPSLC7A5HTR2A | |
| SCHEMBL37182814 | 0.86 | SLC7A5 (0.73) | ANPEPENPEPSLC7A5HTR2A | |
| SCHEMBL9061942 | 0.86 | SLC7A5 (0.48) | ANPEPENPEPSLC7A5MAOAEPHX1 | |
| SCHEMBL9622159 | 0.86 | ANPEP (0.69) | ANPEPENPEPSLC7A5TAAR1SLC6A2 | |
| SCHEMBL1397444 | 0.86 | ANPEP (0.69) | ANPEPENPEPSLC7A5TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060161001-A1 | Substituted heterocyclic compounds and methods of use | AMGEN INC. (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161001-A1 | Substituted heterocyclic compounds and methods of use | MAPT, MYLK2, IAPP | ANPEP 4263/4885ENPEP 3485/4885SLC7A5 4076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.