SCHEMBL16200712

SCHEMBL16200712

c1ccc(-n2c3ccccc3c3cc4c(ccc5cc(-c6ccc7cc(-c8ccc9c%10c(cccc8%10)-c8ccccc8-9)ccc7c6)ccc54)cc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
HIF1A Q16665 1/20 0.37
HSD17B10 Q99714 1/20 0.37
F2 P00734 1/20 0.30
F10 P00742 1/20 0.30
PRSS1 P07477 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17953774 0.92 L3MBTL1 (0.45) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL17953771 0.90 L3MBTL1 (0.45) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL15480054 0.89 L3MBTL1 (0.40) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL16200750 0.89 L3MBTL1 (0.42) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL17341503 0.87 ALDH1A1 (0.42) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL15479987 0.86 L3MBTL1 (0.42) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL17341505 0.86 ALDH1A1 (0.41) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL12716591 0.86 L3MBTL1 (0.51) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL16200694 0.86 L3MBTL1 (0.55) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL17953775 0.85 L3MBTL1 (0.47) L3MBTL1KDM4EATMALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9748490-B2 Organic compound, organic light-emitting element, and image display unit CANON KABUSHIKI KAISHA (JP) 2017-08-29 US disclosed
US-9748490-B2 Organic compound, organic light-emitting element, and image display unit CANON KABUSHIKI KAISHA (JP) 2017-08-29 US disclosed
US-20140319494-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, AND IMAGE DISPLAY UNIT CANON KABUSHIKI KAISHA (JP) 2014-10-30 US disclosed
US-20140319494-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, AND IMAGE DISPLAY UNIT CANON KABUSHIKI KAISHA (JP) 2014-10-30 US disclosed