SCHEMBL16200755

SCHEMBL16200755

CCNc1cc(NC(=O)c2cccc(C)c2)nc(NC(=O)c2ccccc2)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.54
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
KCNK3 O14649 4/20 0.53
KCNK9 Q9NPC2 3/20 0.53
POLB P06746 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
SCD O00767 1/20 0.48
MAPK14 Q16539 2/20 0.47
STAT3 P40763 1/20 0.47
KCNH2 Q12809 1/20 0.47
IDE P14735 1/20 0.46
IKBKB O14920 1/20 0.46
MAPK13 O15264 1/20 0.46
PRKD3 O94806 1/20 0.46
MAP4K4 O95819 1/20 0.46
EGFR P00533 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821395 0.96 GRM5 (0.58) GRM5MEN1KMT2AKCNK3KCNK9
SCHEMBL821945 0.91 L3MBTL1 (0.59) MEN1KMT2ASMN1; SMN2L3MBTL1NPC1
SCHEMBL822364 0.90 KCNK3 (0.58) GRM5MEN1KMT2AKCNK3KCNK9
SCHEMBL822010 0.88 KCNK3 (0.58) GRM5MEN1KMT2AKCNK3KCNK9
SCHEMBL15305709 0.87 GRM5 (0.68) GRM5MEN1KMT2AKCNK3KCNK9
SCHEMBL822355 0.87 GRM5 (0.55) GRM5MEN1KMT2AKCNK3KCNK9
SCHEMBL15305751 0.86 GRM5 (0.58) GRM5MEN1KMT2AKCNK3KCNK9
SCHEMBL15305753 0.86 GRM5 (0.58) GRM5MEN1KMT2AKCNK3KCNK9
SCHEMBL15305737 0.85 GRM5 (0.63) GRM5MEN1KMT2AKCNK3KCNK9
SCHEMBL15305743 0.85 GRM5 (0.63) GRM5MEN1KMT2AKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed