SCHEMBL821945

SCHEMBL821945

CCNc1cc(NC(=O)c2ccccc2)nc(NC(=O)c2ccccc2)n1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
ADORA1 P30542 2/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
ADORA3 P0DMS8 3/20 0.50
NPC1 O15118 6/20 0.48
RAB9A P51151 6/20 0.48
CCNA2 P20248 1/20 0.47
CDK2 P24941 1/20 0.47
CCNA1 P78396 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
EGFR P00533 1/20 0.45
ERBB3 P21860 1/20 0.45
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16200755 0.91 GRM5 (0.54) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL822354 0.89 L3MBTL1 (0.57) L3MBTL1ADORA1MEN1KMT2AADORA3
SCHEMBL822067 0.87 L3MBTL1 (0.54) L3MBTL1ADORA1MEN1KMT2AADORA3
SCHEMBL821395 0.87 GRM5 (0.58) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL821939 0.84 ADORA1 (0.56) L3MBTL1ADORA1MEN1KMT2AADORA3
SCHEMBL10073723 0.83 L3MBTL1 (0.56) L3MBTL1ADORA1MEN1KMT2AADORA3
SCHEMBL822364 0.81 KCNK3 (0.58) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL821779 0.81 NPC1 (0.61) L3MBTL1ADORA1MEN1KMT2AADORA3
SCHEMBL822347 0.80 L3MBTL1 (0.56) L3MBTL1ADORA1MEN1KMT2AADORA3
SCHEMBL822059 0.79 ADORA1 (0.58) L3MBTL1ADORA1MEN1KMT2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9656969-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-9656969-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-20160159750-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2016-06-09 US disclosed
US-20160159750-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2016-06-09 US disclosed
US-9296877-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2016-03-29 US disclosed
US-9296877-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2016-03-29 US disclosed
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-20120268694-A1 CELLULOSE ACYLATE FILM, METHOD FOR PRODUCING SAME, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-25 US disclosed
US-20120249933-A1 CELLULOSE ACYLATE FILM, ITS PRODUCTION METHOD, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-04 US disclosed
US-20120231217-A1 OPTICAL FILM, PHASE DIFFERENCE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-20120204757-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
US-20120180697-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-19 US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160159750-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND PYM1, CNKSR1, MYB L3MBTL1 2060/4885ADORA1 1640/4885MEN1 1019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.