Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10299778 | 1.00 | PDE4A (0.41) | PDE4ALMNAL3MBTL1KDM4ETDP1 | |
| SCHEMBL25262519 | 0.90 | PDE4A (0.42) | PDE4ALMNAL3MBTL1KDM4ETDP1 | |
| SCHEMBL10601522 | 0.84 | PDE4A (0.46) | PDE4ALMNAL3MBTL1KDM4ETDP1 | |
| SCHEMBL29386817 | 0.81 | PDE4A (0.43) | PDE4ALMNAL3MBTL1KDM4ETDP1 | |
| SCHEMBL8528869 | 0.80 | KDM4E (0.48) | PDE4ALMNAL3MBTL1KDM4ETDP1 | |
| SCHEMBL10299846 | 0.80 | KDM4E (0.48) | PDE4ALMNAL3MBTL1KDM4ETDP1 | |
| SCHEMBL444014 | 0.80 | KDM4E (0.48) | PDE4ALMNAL3MBTL1KDM4ETDP1 | |
| SCHEMBL10476971 | 0.79 | ALDH1A1 (0.41) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL30398967 | 0.79 | ALDH1A1 (0.41) | PDE4ALMNAUSP2SLCO1B1CYP2C9 | |
| SCHEMBL23531048 | 0.79 | ALDH1A1 (0.41) | PDE4ALMNAL3MBTL1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140322723-A1 | DIABETES DIAGNOSIS THROUGH THE DETECTION OF GLYCATED PROTEINS IN URINE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2014-10-30 | — | — | US | disclosed |