SCHEMBL444014

SCHEMBL444014

CNCC(=O)[C@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
PDE4A P27815 1/20 0.43
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
USP2 O75604 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8528869 1.00 KDM4E (0.48) KDM4EPDE4ALMNAL3MBTL1TDP1
SCHEMBL10299846 1.00 KDM4E (0.48) KDM4EPDE4ALMNAL3MBTL1TDP1
Hydrochloric Acid SCHEMBL8528184 0.98 KDM4E (0.47) KDM4EPDE4ALMNAL3MBTL1TDP1
SCHEMBL25262519 0.82 PDE4A (0.42) KDM4EPDE4ALMNAL3MBTL1TDP1
SCHEMBL10299778 0.80 PDE4A (0.41) KDM4EPDE4ALMNAL3MBTL1TDP1
SCHEMBL11350754 0.80 PDE4A (0.41) KDM4EPDE4ALMNAL3MBTL1TDP1
SCHEMBL8532266 0.80 PDE4A (0.41) KDM4EPDE4ALMNAL3MBTL1TDP1
SCHEMBL16201531 0.80 PDE4A (0.41) KDM4EPDE4ALMNAL3MBTL1TDP1
SCHEMBL11414474 0.80 PDE4A (0.41) KDM4EPDE4ALMNAL3MBTL1TDP1
SCHEMBL8829389 0.79 PDE4A (0.43) KDM4EPDE4ALMNAL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2515850-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING CEFDINIR AS AN ACTIVE AGENT BILGIC MAHMUT (TR) 2016-06-29 EP claimed
EP-2780748-B1 A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING NOVARTIS AG (CH) 2016-01-13 EP claimed
EP-2515860-B1 IMPROVED PHARMACEUTICAL COMPOSITIONS COMPRISING CEFDINIR BILGIC MAHMUT (TR) 2015-07-29 EP claimed
EP-2718751-B1 SILICONE HYDROGEL LENSES WITH NANO-TEXTURED SURFACES NOVARTIS AG (CH) 2015-07-22 EP claimed
EP-2516448-B1 AMINE SALTS OF CEFDINIR BILGIC MAHMUT (TR) 2015-04-15 EP claimed
EP-2780748-A1 A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING Novartis AG (CH) 2014-09-24 EP claimed
EP-2718751-A1 SILICONE HYDROGEL LENSES WITH NANO-TEXTURED SURFACES Novartis AG (CH) 2014-04-16 EP claimed
US-20140079647-A1 CEFDINIR AND CEFIXIME FORMULATIONS AND USES THEREOF BILGIC MAHMUT (TR) 2014-03-20 US claimed
US-8614315-B2 Cefdinir and cefixime formulations and uses thereof BILGIC MAHMUT (TR) 2013-12-24 US claimed
WO-2013074535-A1 A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING NOVARTIS AG (CH) 2013-05-23 WO claimed
US-20130017156-A1 CEFDINIR AND CEFIXIME FORMULATIONS AND USES THEREOF BILGIC MAHMUT (TR) 2013-01-17 US claimed
WO-2012170603-A1 SILICONE HYDROGEL LENSES WITH NANO-TEXTURED SURFACES NOVARTIS AG (CH) 2012-12-13 WO claimed
EP-4720728-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4707877-A2 METHOD FOR PRODUCING SILICON HYDROGEL CONTACT LENSES WITH CROSSLINKED HYDROPHILIC COATINGS THEREON Alcon Inc. (CH) 2026-03-11 EP disclosed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US disclosed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US disclosed
US-5747468-A Cationic unsaturated saccharides and polymers prepared therefrom, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1998-05-05 US disclosed
US-4307072-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1981-12-22 US disclosed
US-4224440-A NON-IONIC X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1980-09-23 US disclosed
US-4109081-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1978-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES CRYZ, STRA6, PHOSPHO1 KDM4E 1450/4885PDE4A 2929/4885LMNA 214/4885
US-20140079647-A1 CEFDINIR AND CEFIXIME FORMULATIONS AND USES THEREOF C1R, CFD, CSF3R KDM4E 2705/4885PDE4A 495/4885LMNA 3993/4885
US-20130017156-A1 CEFDINIR AND CEFIXIME FORMULATIONS AND USES THEREOF C1R, CFD, CSF3R KDM4E 2705/4885PDE4A 495/4885LMNA 3993/4885
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES STRA6, CRYZ, SMCHD1 KDM4E 1841/4885PDE4A 3999/4885LMNA 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.