Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | PORCN | Q9H237 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322831 | 0.80 | CYP11B1 (0.57) | CYP11B1CYP11B2COMTPIK3CDPIK3CA | |
| SCHEMBL30551409 | 0.80 | CYP11B1 (0.57) | CYP11B1CYP11B2COMTPIK3CDPIK3CA | |
| SCHEMBL21258382 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2COMTPIK3CDPIK3CA | |
| SCHEMBL31148179 | 0.78 | COMT (0.43) | CYP11B1CYP11B2COMTPIK3CDPIK3CA | |
| SCHEMBL1460480 | 0.76 | EGLN2 (0.50) | CYP11B1CYP11B2COMTPORCNCYP2D6 | |
| SCHEMBL12935411 | 0.76 | CYP11B1 (0.47) | CYP11B1CYP11B2COMTPORCNCYP2D6 | |
| SCHEMBL29620872 | 0.75 | CYP11B1 (0.46) | CYP11B1CYP11B2COMTPORCNCYP2D6 | |
| SCHEMBL14938310 | 0.75 | PORCN (0.58) | CYP11B1CYP11B2COMTPIK3CDPIK3CA | |
| SCHEMBL14167514 | 0.75 | CYP11B1 (0.46) | CYP11B1CYP11B2COMTPORCNCYP2D6 | |
| SCHEMBL16826278 | 0.73 | CYP3A4 (0.53) | COMTPIK3CDPIK3CAPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695236-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024216094-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |
| WO-2014175832-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-10-30 | — | — | WO | disclosed |