Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 9/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14167514 | 1.00 | CYP11B1 (0.46) | CYP11B1CYP11B2CYP1A2METAP2NPSR1 | |
| SCHEMBL20449134 | 0.77 | CYP1A2 (0.46) | CYP11B1CYP11B2CYP1A2METAP2NPSR1 | |
| SCHEMBL14938229 | 0.76 | CYP1A2 (0.49) | CYP1A2METAP2OXTRAVPR1AKIF11 | |
| SCHEMBL30551409 | 0.76 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP1A2METAP2KDM4E | |
| SCHEMBL25322831 | 0.76 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP1A2METAP2KDM4E | |
| SCHEMBL14762177 | 0.75 | CYP11B2 (0.44) | CYP11B1CYP11B2CYP1A2METAP2COMT | |
| SCHEMBL16201537 | 0.75 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP1A2COMTCYP2D6 | |
| SCHEMBL21258382 | 0.75 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP1A2PDE2ACOMT | |
| SCHEMBL29454964 | 0.74 | KDM4E (0.44) | CYP1A2NPSR1KDM4EPDE2AKIF11 | |
| SCHEMBL29595709 | 0.74 | NPSR1 (0.53) | NPSR1KDM4EKIF11CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |