Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13056651 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15KDM4EUSP2 | |
| SCHEMBL22070686 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TSHRALOX15KDM4EUSP2 | |
| SCHEMBL4472128 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRALOX15KDM4EUSP2 | |
| SCHEMBL21070696 | 0.82 | TSHR (0.67) | ALDH1A1TSHRALOX15KDM4EUSP2 | |
| SCHEMBL13056658 | 0.81 | EPHX2 (0.44) | ALDH1A1TSHRALOX15KDM4EUSP2 | |
| SCHEMBL16202244 | 0.81 | MEN1 (0.47) | ALDH1A1TSHREPHX2POLBCYP4F2 | |
| SCHEMBL27160297 | 0.81 | EPHX2 (0.44) | ALDH1A1TSHRALOX15KDM4EUSP2 | |
| SCHEMBL27160293 | 0.80 | EPHX2 (0.46) | ALDH1A1TSHREPHX2POLBCYP4F2 | |
| SCHEMBL17744972 | 0.80 | TSHR (0.62) | ALDH1A1TSHRALOX15KDM4EUSP2 | |
| SCHEMBL13056648 | 0.79 | EPHX2 (0.48) | ALDH1A1TSHREPHX2POLBCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9719986-B2 | Haptens, hapten conjugates, compositions thereof preparation and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-20140323336-A1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-10-30 | — | — | US | disclosed |