Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13056649 | 1.00 | KDM4E (0.48) | KDM4EMAPK1HIF1AUSP2ALDH1A1 | |
| SCHEMBL11840924 | 0.84 | TSHR (0.54) | KDM4EMAPK1HIF1AUSP2ALDH1A1 | |
| SCHEMBL14524171 | 0.81 | ALDH1A1 (0.40) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL22340557 | 0.80 | KDM4E (0.64) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL3706965 | 0.80 | ALDH1A1 (0.46) | KDM4EMAPK1HIF1AUSP2ALDH1A1 | |
| SCHEMBL5693542 | 0.80 | KDM4E (0.61) | KDM4EMAPK1HIF1AALDH1A1TSHR | |
| SCHEMBL5572140 | 0.79 | TDP1 (0.55) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL16202243 | 0.79 | MAPK1 (0.56) | KDM4EMAPK1HIF1ATSHRPAOX | |
| SCHEMBL21070696 | 0.78 | TSHR (0.67) | KDM4EMAPK1USP2ALDH1A1LMNA | |
| SCHEMBL13056651 | 0.77 | ALDH1A1 (0.50) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9719986-B2 | Haptens, hapten conjugates, compositions thereof preparation and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-20140323336-A1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-10-30 | — | — | US | disclosed |