SCHEMBL162040

SCHEMBL162040

Oc1cc2ccccc2c(O)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.48
NQO2 P16083 1/20 0.46
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 3/20 0.42
HIF1A Q16665 1/20 0.42
CYP1B1 Q16678 1/20 0.42
CYP1A2 P05177 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
HPGD P15428 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
MPI P34949 1/20 0.41
GLA P06280 1/20 0.40
CYP2C19 P33261 1/20 0.40
ALOX5 P09917 1/20 0.39
PTPN22 Q9Y2R2 1/20 0.38
CYP2A6 P11509 2/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9629001 0.81 TRPM4 (0.48) TRPM4NQO2ALDH1A1HSD17B10HIF1A
SCHEMBL11323520 0.79 HPRT1 (0.50) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL1133961 0.77 TRPM4 (0.45) TRPM4NQO2ALDH1A1HSD17B10HIF1A
SCHEMBL14913815 0.77 TRPM4 (0.45) TRPM4NQO2ALDH1A1HSD17B10HIF1A
SCHEMBL13542119 0.77 TRPM4 (0.45) TRPM4NQO2ALDH1A1HSD17B10HIF1A
SCHEMBL3083764 0.77 TRPM4 (0.45) TRPM4NQO2ALDH1A1HSD17B10HIF1A
SCHEMBL7882102 0.77 TRPM4 (0.45) TRPM4NQO2ALDH1A1HSD17B10HIF1A
SCHEMBL1133568 0.77 PLAU (0.47) TRPM4NQO2ALDH1A1HSD17B10HIF1A
SCHEMBL20977726 0.77 TRPM4 (0.45) TRPM4NQO2ALDH1A1HSD17B10HIF1A
SCHEMBL28347820 0.77 TRPM4 (0.45) TRPM4NQO2ALDH1A1HSD17B10HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250186323-A1 COMPOSITION FOR SKIN WHITENING COMPRISING CARVEDILOL GMEX (GLOBAL MEDICAL XYNAPSE) (KR) 2025-06-12 US claimed
US-20230150924-A1 NOVEL COMPOUND HAVING CANCER METASTASIS INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR INHIBITING CANCER METASTASIS AND INVASION OR TREATING COLORECTAL CANCER, COMPRISING COMPOUND CELLGENTEK CO., LTD. (KR) 2023-05-18 US claimed
EP-4019495-A1 NOVEL COMPOUND HAVING CANCER METASTASIS INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR INHIBITING CANCER METASTASIS AND INVASION OR TREATING COLORECTAL CANCER, COMPRISING COMPOUND Cellgentek Co., Ltd (KR) 2022-06-29 EP claimed
US-10987296-B2 Composition for improving skin wrinkle containing exopolysaccharide produced by Ceriporia lacerata as active ingredient FUGENBIO CO., LTD. (KR) 2021-04-27 US claimed
WO-2021034087-A1 NOVEL COMPOUND HAVING CANCER METASTASIS INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR INHIBITING CANCER METASTASIS AND INVASION OR TREATING COLORECTAL CANCER, COMPRISING COMPOUND 주식회사 셀젠텍 2021-02-25 WO claimed
US-10479787-B2 Process for preparation of tetrabenazine and deutetrabenazine LUPIN LIMITED (IN) 2019-11-19 US claimed
US-20190135803-A1 NOVEL PROCESS FOR PREPARATION OF TETRABENAZINE AND DEUTETRABENAZINE LUPIN LIMITED (IN) 2019-05-09 US claimed
US-20190008748-A1 COMPOSITION FOR IMPROVING SKIN CONDITION CONTAINING EXOPOLYSACCHARIDE PRODUCED BY CERIPORIA LACERATA AS ACTIVE INGREDIENT FUGENBIO CO., LTD. (KR) 2019-01-10 US claimed
WO-2017182916-A1 NOVEL PROCESS FOR PREPARATION OF TETRABENAZINE AND DEUTETRABENAZINE LUPIN LIMITED (IN) 2017-10-26 WO claimed
CN-105399669-A Dihydroxy isoquinoline and preparation method and application thereof from centipedes UNIV CHINA PHARMA 2016-03-16 CN claimed
CN-105294561-A Type of isoquinoline as well as preparation method and application thereof UNIV CHINA PHARMA 2016-02-03 CN claimed
EP-1962843-B1 USE OF PARP-1 INHIBITORS PHARMA MAR SA (ES) 2011-02-23 EP claimed
EP-1237871-A2 NOVEL SUBSTITUTED PHENANTHRIDINONES AND METHODS OF USE THEREOF Inotek Corporation (US) 2002-09-11 EP claimed
WO-2001042219-A2 NOVEL SUBSTITUTED PHENANTHRIDINONES AND METHODS OF USE THEREOF INOTEK CORPORATION (US) 2001-06-14 WO claimed
WO-1999008680-A1 METHOD OF USING SELECTIVE PARP INHIBITORS TO PREVENT OR TREAT NEUROTOXICITY THE JOHNS HOPKINS UNIVERSITY (US) 1999-02-25 WO claimed
WO-1998027975-A1 POLY(ADP-RIBOSE) POLYMERASE INHIBITORS TO TREAT DISEASES ASSOCIATED WITH CELLULAR SENESCENCE GERON CORPORATION (US) 1998-07-02 WO claimed
EP-0238060-B1 CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS Banyu Pharmaceutical Co., Ltd. (JP) 1992-01-08 EP claimed
JP-1259033-A None JP disclosed
US-4116953-A 2-PHENYL-3,1-BENZOXAZIN-4-ONES, PIGMENTS BASF AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed
US-4016151-A Phenyl-substituted phthalazone azo dyes with a coupling component of the phenol, napthol, acetoacetarylide, pyrazolone, quinolone, pyridine, pyrimidone or isoquinolone series BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190135803-A1 NOVEL PROCESS FOR PREPARATION OF TETRABENAZINE AND DEUTETRABENAZINE KAT5, KAT2A, KAT2B TRPM4 1204/4885NQO2 1650/4885ALDH1A1 627/4885
US-20250186323-A1 COMPOSITION FOR SKIN WHITENING COMPRISING CARVEDILOL TYR, CREBBP, MITF TRPM4 585/4885NQO2 2800/4885ALDH1A1 1715/4885
US-20230150924-A1 NOVEL COMPOUND HAVING CANCER METASTASIS INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR INHIBITING CANCER METASTASIS AND INVASION OR TREATING COLORECTAL CANCER, COMPRISING COMPOUND KNTC1, MED1, LEF1 TRPM4 1845/4885NQO2 3817/4885ALDH1A1 1404/4885
US-10479787-B2 Process for preparation of tetrabenazine and deutetrabenazine KAT5, KAT2A, KAT2B TRPM4 1495/4885NQO2 1553/4885ALDH1A1 659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.