Sugi Predict

Sugi Predict / Compounds / Formic Acid

Formic Acid

Formic Acid

SCHEMBL16205011

O=C(O)NC(c1ccccc1)c1cccc(OCc2cccc(CCNCC(O)c3ccc(O)c4[nH]c(=O)ccc34)c2)c1.O=CO

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ADRB2 P07550 14/20 0.65
▸ CHRM3 P20309 10/20 0.65
▸ ADRB1 P08588 4/20 0.56
▸ ADRA1D P25100 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL16205008 1.00 ADRB2 (0.65) ADRB2CHRM3ADRB1ADRA1D
SCHEMBL15777982 0.98 ADRB2 (0.67) ADRB2CHRM3ADRB1ADRA1D
SCHEMBL15777980 0.98 ADRB2 (0.67) ADRB2CHRM3ADRB1ADRA1D
SCHEMBL17082532 0.98 ADRB2 (0.67) ADRB2CHRM3ADRB1ADRA1D
SCHEMBL15777978 0.98 ADRB2 (0.67) ADRB2CHRM3ADRB1ADRA1D
SCHEMBL20357860 0.98 ADRB2 (0.67) ADRB2CHRM3ADRB1ADRA1D
SCHEMBL16205030 0.93 ADRB2 (0.74) ADRB2CHRM3ADRB1
SCHEMBL16205035 0.93 ADRB2 (0.74) ADRB2CHRM3ADRB1
SCHEMBL16205033 0.93 ADRB2 (0.74) ADRB2CHRM3ADRB1
SCHEMBL16205036 0.92 ADRB2 (0.61) ADRB2CHRM3ADRB1ADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2718280-B1 COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY CHIESI FARMA SPA (IT) 2015-09-16 — — EP claimed
US-8877774-B2 Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity CHIESI FARMACEUTICI S.P.A. (IT) 2014-11-04 — — US claimed
Send feedback