Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16205109 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPK8MAPK9ARALDH1A1 | |
| SCHEMBL15566902 | 0.85 | CTDSP1 (0.39) | SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL15566899 | 0.85 | CTDSP1 (0.39) | SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL16204938 | 0.84 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL16204937 | 0.84 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL621974 | 0.82 | KMT2A (0.40) | SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL621976 | 0.82 | KMT2A (0.40) | SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL17363074 | 0.76 | MRGPRX4 (0.31) | MAPK8MAPK9MRGPRX4 | |
| SCHEMBL15972526 | 0.75 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPK8MAPK9ALDH1A1GAA | |
| SCHEMBL17363040 | 0.75 | TP53 (0.31) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3593648-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-2880031-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2020-06-17 | — | — | EP | disclosed |
| US-9745293-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-20170183336-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9687015-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160331013-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2016-11-17 | — | — | US | disclosed |
| US-9420814-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150374020-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2015-12-31 | — | — | US | disclosed |
| US-9138013-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150031684-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC | 2015-01-29 | — | — | US | disclosed |
| US-8877922-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2014-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374020-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | SMN1; SMN2 3389/4885MAPK8 4436/4885MAPK9 4017/4885 |
| US-20150031684-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | SMN1; SMN2 3389/4885MAPK8 4436/4885MAPK9 4017/4885 |
| US-20170183336-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | SMN1; SMN2 3349/4885MAPK8 4403/4885MAPK9 4042/4885 |
| US-20160331013-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | SMN1; SMN2 3349/4885MAPK8 4403/4885MAPK9 4042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.