SCHEMBL16205161

SCHEMBL16205161

C=C(C)C(=O)OC(CC)[Si](O[Si](c1ccccc1)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.34
MAPT P10636 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6912808 0.88 ELANE (0.35) ELANEMAPTALDH1A1HPGDPOLB
SCHEMBL1398278 0.87 MAPT (0.35) ELANEMAPTALDH1A1HPGD
SCHEMBL6039959 0.82 ELANE (0.38) ELANEMAPTALDH1A1HPGDPOLB
SCHEMBL4661542 0.81 ELANE (0.37) ELANEMAPTALDH1A1HPGDPOLB
SCHEMBL4661369 0.81 ELANE (0.37) ELANEMAPTALDH1A1HPGDPOLB
SCHEMBL28231244 0.78 ELANE (0.35) ELANEMAPTALDH1A1HPGD
SCHEMBL393902 0.78 ELANE (0.33) ELANEMAPTALDH1A1HPGD
SCHEMBL3132567 0.77 MAPT (0.35) ELANEMAPTALDH1A1HPGDTDP1
Toluene SCHEMBL28206094 0.72 ALDH1A1 (0.35) ELANEMAPTALDH1A1POLBTDP1
SCHEMBL9223519 0.72 ELANE (0.39) ELANEMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052140-B1 NON-SELF-ADHERENT COATING MATERIALS ROCHAL IND LLC (US) 2019-05-01 EP disclosed
US-8877882-B1 Non-self-adherent coating materials ROCHAL INDUSTRIES LLP (US) 2014-11-04 US disclosed