Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16205161 | 0.88 | ELANE (0.34) | ELANEMAPTALDH1A1HPGDPOLB | |
| SCHEMBL1398278 | 0.88 | MAPT (0.35) | ELANEMAPTALDH1A1HPGD | |
| SCHEMBL393902 | 0.87 | ELANE (0.33) | ELANEMAPTALDH1A1HPGD | |
| SCHEMBL6039959 | 0.83 | ELANE (0.38) | ELANEMAPTALDH1A1HPGDLMNA | |
| SCHEMBL4661369 | 0.82 | ELANE (0.37) | ELANEMAPTALDH1A1HPGDPOLB | |
| SCHEMBL4661542 | 0.82 | ELANE (0.37) | ELANEMAPTALDH1A1HPGDPOLB | |
| SCHEMBL28231244 | 0.80 | ELANE (0.35) | ELANEMAPTALDH1A1HPGD | |
| SCHEMBL3132567 | 0.78 | MAPT (0.35) | ELANEMAPTALDH1A1HPGD | |
| Toluene SCHEMBL28206094 | 0.78 | ALDH1A1 (0.35) | ELANEMAPTALDH1A1KLK7POLB | |
| SCHEMBL65879 | 0.76 | TSHR (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465903-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003040158-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |