SCHEMBL16205209

SCHEMBL16205209

NCCCCCCCCCCCNc1nc2[nH]cnc2c(=O)[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 3/20 0.50
PIM1 P11309 2/20 0.47
GPR84 Q9NQS5 1/20 0.36
PNP P00491 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PRKD3 O94806 3/20 0.33
PRKCG P05129 3/20 0.33
PRKCB P05771 3/20 0.33
PRKCA P17252 3/20 0.33
PRKCH P24723 3/20 0.33
PRKCI P41743 3/20 0.33
PRKCE Q02156 3/20 0.33
PRKCQ Q04759 3/20 0.33
PRKCZ Q05513 3/20 0.33
PRKCD Q05655 3/20 0.33
PRKD1 Q15139 3/20 0.33
PRKACA P17612 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21183279 0.89 XDH (0.44) XDHPIM1PNPALDH1A1KDM4E
SCHEMBL8535455 0.86 XDH (0.67) XDHGPR84ALDH1A1KDM4E
SCHEMBL249648 0.85 XDH (0.66) XDHGPR84ALDH1A1KDM4E
SCHEMBL2623143 0.83 XDH (0.65) XDHGPR84ALDH1A1KDM4E
SCHEMBL10047094 0.83 XDH (0.40) XDHPNPALDH1A1KDM4E
SCHEMBL26174316 0.80 XDH (0.53) XDHGPR84PNPALDH1A1KDM4E
SCHEMBL23133118 0.80 XDH (0.48) XDHGPR84PNPALDH1A1SMN1; SMN2
SCHEMBL16197989 0.80 XDH (0.77) XDH
SCHEMBL21258890 0.80 XDH (0.41) XDHPNPALDH1A1SMN1; SMN2KDM4E
SCHEMBL1965514 0.79 XDH (0.47) XDHGPR84ALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014175836-A1 MODIFIED G-QUADRUPLEX NANOPARTICLES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2014-10-30 WO disclosed