Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 11/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.39 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249648 | 0.99 | XDH (0.66) | XDHGPR84KDM4EALDH1A1RIPK1 | |
| SCHEMBL2623143 | 0.94 | XDH (0.65) | XDHGPR84KDM4EALDH1A1RIPK1 | |
| SCHEMBL26174316 | 0.89 | XDH (0.53) | XDHGPR84KDM4EALDH1A1RIPK1 | |
| SCHEMBL16205209 | 0.86 | XDH (0.50) | XDHGPR84KDM4EALDH1A1 | |
| SCHEMBL10047127 | 0.85 | XDH (0.51) | XDHGPR84KDM4EALDH1A1RIPK1 | |
| SCHEMBL5062459 | 0.83 | XDH (0.46) | XDHKDM4EALDH1A1 | |
| SCHEMBL23133118 | 0.83 | XDH (0.48) | XDHGPR84KDM4EALDH1A1RIPK1 | |
| SCHEMBL1965514 | 0.82 | XDH (0.47) | XDHGPR84KDM4EALDH1A1RIPK1 | |
| SCHEMBL10047126 | 0.82 | XDH (0.50) | XDHGPR84KDM4EALDH1A1RIPK1 | |
| SCHEMBL21183279 | 0.80 | XDH (0.44) | XDHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | disclosed |