Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898966 | 1.00 | CA12 (0.62) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL30323518 | 0.97 | CA12 (0.59) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL30323660 | 0.97 | CA12 (0.59) | CA12CA7CA14SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL9002579 | 0.97 | CA12 (0.59) | CA12CA7CA14SMN1; SMN2TSHR | |
| Ethane SCHEMBL28543734 | 0.87 | CA12 (0.48) | CA12CA7CA14SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL27781421 | 0.82 | CA12 (0.48) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL15935734 | 0.79 | CA12 (0.56) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL973439 | 0.78 | POLB (0.40) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL1746338 | 0.78 | — | — | |
| SCHEMBL4724826 | 0.77 | CA12 (1.00) | CA12CA7CA14SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799437-B1 | QUINOLINE AND CINNOLINE DERIVATIVES AND USE THEREOF | UNIV SHENYANG PHARMACEUTICAL (CN) | 2016-09-14 | — | — | EP | claimed |
| US-9382232-B2 | Quinoline and cinnoline derivatives and their applications | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-07-05 | — | — | US | claimed |
| US-20140364431-A1 | Quinoline and cinnoline derivatives and their applications | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2014-12-11 | — | — | US | claimed |
| EP-2799437-A1 | QUINOLINE AND CINNOLINE COMPOUNDS AND USE THEREOF | Shenyang Pharmaceutical University (CN) | 2014-11-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364431-A1 | Quinoline and cinnoline derivatives and their applications | MET, CHEK1, KIT | CA12 967/4885CA7 8/4885CA14 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.