Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Ethane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16207447 | 0.87 | CA12 (0.62) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL898966 | 0.87 | CA12 (0.62) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL30323660 | 0.84 | CA12 (0.59) | CA12CA7CA14SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL9002579 | 0.84 | CA12 (0.59) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL30323518 | 0.84 | CA12 (0.59) | CA12CA7CA14SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL27781421 | 0.76 | CA12 (0.48) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL7602303 | 0.75 | CA12 (0.59) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL9608598 | 0.72 | CA12 (0.50) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL27715673 | 0.72 | ALDH1A1 (0.45) | CA12CA7CA14SMN1; SMN2TSHR | |
| SCHEMBL9608587 | 0.71 | LMNA (0.50) | CA12CA7CA14SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108043246-B | Preparation method of super-hydrophilic organic membrane based on micro-nano structure surface imprinting | 北京林业大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-108079798-B | Preparation method of super-hydrophilic organic membrane based on nano hydrotalcite-like compound | 北京林业大学 | 2021-04-13 | — | — | CN | disclosed |
| CN-107998908-B | Preparation method of super-hydrophilic organic membrane based on micro-nano substrate | 北京林业大学 | 2021-04-13 | — | — | CN | disclosed |