Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16215853 | 0.82 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL16207699 | 0.82 | P2RX7 (0.54) | HRH3KCNH2 | |
| SCHEMBL16207739 | 0.81 | HRH3 (0.48) | HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL16207754 | 0.81 | HRH3 (0.57) | HRH3KCNH2 | |
| SCHEMBL16207745 | 0.81 | ACKR3 (0.51) | HRH3KCNH2 | |
| SCHEMBL16207620 | 0.81 | HRH3 (0.50) | MIFHRH3 | |
| SCHEMBL16207696 | 0.80 | ACKR3 (0.53) | HRH3 | |
| SCHEMBL16207762 | 0.80 | HRH3 (0.47) | HRH3KCNH2 | |
| SCHEMBL16207579 | 0.80 | HRH3 (0.48) | HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL16207786 | 0.80 | ACKR3 (0.50) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150045553-A1 | PHENYLTRIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2015-02-12 | — | — | US | disclosed |
| US-20150045553-A1 | PHENYLTRIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2015-02-12 | — | — | US | disclosed |
| US-20150045553-A1 | PHENYLTRIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2015-02-12 | — | — | US | disclosed |
| EP-2799436-A1 | PHENYLTRIAZOLE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045553-A1 | PHENYLTRIAZOLE DERIVATIVE | PER2, BACE1, MAPT | MIF 3131/4885HRH3 56/4885KCNH2 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.