Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.40 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 7/20 | 0.39 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6520541 | 0.90 | NR4A2 (0.61) | NR4A2MAPTTP53GAAALDH1A1 | |
| SCHEMBL6519571 | 0.81 | NR4A2 (0.50) | NR4A2MAPTSLC2A1SLC2A2TOP2A | |
| SCHEMBL2064008 | 0.79 | NR4A2 (1.00) | NR4A2MAPTALDH1A1 | |
| SCHEMBL6521387 | 0.79 | NR4A2 (0.51) | NR4A2MAPTSLC2A1 | |
| SCHEMBL6527443 | 0.78 | NR4A2 (0.47) | NR4A2MAPTGAAALDH1A1SLC2A1 | |
| SCHEMBL3431442 | 0.77 | NR4A2 (0.47) | NR4A2MAPTTP53GAAALDH1A1 | |
| SCHEMBL3431629 | 0.74 | NR4A2 (0.46) | NR4A2TP53GAASLC2A1 | |
| SCHEMBL6523781 | 0.72 | CYP2C9 (0.62) | NR4A2SLC2A1SLC2A2TOP2A | |
| SCHEMBL3430036 | 0.71 | NR4A2 (0.79) | NR4A2MAPTALDH1A1SLC2A1MEN1 | |
| SCHEMBL2064134 | 0.70 | NR4A2 (0.84) | NR4A2ALDH1A1SLC2A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262769-B1 | POLYSUBSTITUTED 2-ARYL-6-PHENYL-IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-11-05 | — | — | EP | claimed |
| EP-2262769-B1 | POLYSUBSTITUTED 2-ARYL-6-PHENYL-IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-11-05 | — | — | EP | disclosed |