Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 14/20 | 1.00 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.56 |
| ▸ | ULK1 | O75385 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16208517 | 0.84 | KIF11 (0.72) | KIF11CRBNPKMMAPT | |
| SCHEMBL16208498 | 0.83 | KIF11 (0.71) | KIF11CRBNULK1PKM | |
| SCHEMBL16208463 | 0.81 | KIF11 (1.00) | KIF11ULK1PKMPKLR | |
| SCHEMBL30122307 | 0.81 | KIF11 (0.73) | KIF11PKMMAPTSMN1; SMN2PKLR | |
| SCHEMBL3468129 | 0.81 | KIF11 (0.69) | KIF11MAPTSMN1; SMN2 | |
| SCHEMBL28956489 | 0.81 | KIF11 (0.73) | KIF11PKMMAPTSMN1; SMN2PKLR | |
| SCHEMBL16208480 | 0.79 | KIF11 (0.72) | KIF11CRBNULK1PKM | |
| SCHEMBL16208488 | 0.78 | KIF11 (1.00) | KIF11CRBNULK1PKMPKLR | |
| SCHEMBL16208500 | 0.77 | KIF11 (0.67) | KIF11CRBNPKM | |
| SCHEMBL16208502 | 0.77 | KIF11 (0.67) | KIF11CRBNULK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014174745-A1 | Eg5 INHIBITOR | 国立大学法人京都大学 (JP) | 2014-10-30 | — | — | WO | disclosed |