Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.81 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | DDX3X | O00571 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | ARNT | P27540 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841678 | 0.92 | KIF11 (0.78) | KIF11MPOMEN1MAPTKMT2A | |
| SCHEMBL7043192 | 0.89 | KIF11 (1.00) | KIF11MPOMEN1MAPTKMT2A | |
| SCHEMBL17103663 | 0.85 | MEN1 (0.75) | KIF11MPOMEN1MAPTKMT2A | |
| SCHEMBL439710 | 0.85 | TSHR (0.61) | KIF11MPOMEN1MAPTKMT2A | |
| SCHEMBL29703748 | 0.85 | TSHR (0.61) | KIF11MPOMEN1MAPTKMT2A | |
| SCHEMBL394734 | 0.85 | KMT2A (0.67) | KIF11MEN1MAPTKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL155429 | 0.83 | KIF11 (0.59) | KIF11MPOMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL155430 | 0.83 | KIF11 (0.59) | KIF11MPOMEN1MAPTKMT2A | |
| SCHEMBL29203888 | 0.83 | KIF11 (0.59) | KIF11MPOMEN1MAPTKMT2A | |
| SCHEMBL30865102 | 0.83 | KIF11 (0.59) | KIF11MPOMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014174745-A1 | Eg5 INHIBITOR | 国立大学法人京都大学 (JP) | 2014-10-30 | — | — | WO | disclosed |