Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16210017 | 1.00 | FAAH (0.50) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL16210018 | 1.00 | FAAH (0.50) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL16209691 | 1.00 | FAAH (0.50) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL8992206 | 0.90 | TSHR (0.39) | FAAHTRPV1TSHRCYP1A2MAPT | |
| SCHEMBL16209865 | 0.85 | FAAH (0.50) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL16209866 | 0.85 | FAAH (0.50) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL296578 | 0.85 | FAAH (0.50) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL296579 | 0.85 | FAAH (0.50) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL6293783 | 0.82 | FAAH (0.52) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL571547 | 0.81 | FAAH (0.52) | FAAHTRPV1TSHRTERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2994474-B1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | MOMENTIVE PERFORMANCE MAT INC (US) | 2017-12-20 | — | — | EP | disclosed |
| US-9371339-B2 | Saturated and unsaturated silahydrocarbons via iron and cobalt pyridine diimine catalyzed olefin silylation | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-06-21 | — | — | US | disclosed |
| EP-2994474-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | Momentive Performance Materials Inc. (US) | 2016-03-16 | — | — | EP | disclosed |
| US-20140330036-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | PRINCETON UNIVERSITY (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330036-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | YAP1, LATS1, SIK1 | FAAH 1521/4885TRPV1 225/4885TSHR 4013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.