⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10090593 | 0.78 | — | — | |
| SCHEMBL10090592 | 0.77 | NPC1 (0.32) | — | |
| SCHEMBL10090591 | 0.77 | BCL2L1 (0.36) | — | |
| SCHEMBL793568 | 0.76 | ALOX15 (0.30) | — | |
| SCHEMBL13156600 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL20044956 | 0.71 | CACNA2D1 (0.35) | — | |
| SCHEMBL336442 | 0.71 | CACNA2D1 (0.37) | — | |
| SCHEMBL29360481 | 0.71 | CACNA2D1 (0.37) | — | |
| SCHEMBL15583659 | 0.70 | — | — | |
| SCHEMBL18267813 | 0.69 | CACNA2D1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190008788-A1 | PROCESS FOR ENCAPSULATING SOLUBLE BIOLOGICS, THERAPEUTICS, AND IMAGING AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-01-10 | — | — | US | disclosed |
| US-10016517-B2 | Bioactive amphiphilic polymer stabilized nanoparticles with enhanced stability and activity | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-07-10 | — | — | US | disclosed |
| US-20140328763-A1 | BIOACTIVE AMPHIPHILIC POLYMER STABILIZED NANOPARTICLES WITH ENHANCED STABILITY AND ACTIVITY | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-11-06 | — | — | US | disclosed |