Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Testosterone Cypionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR known ✓ | P10275 | 5/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.76 |
| ▸ | LMNA | P02545 | 8/20 | 0.76 |
| ▸ | TSHR | P16473 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | PGR | P06401 | 5/20 | 0.76 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.76 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.76 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | SHBG | P04278 | 4/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | SNCA | P37840 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Testosterone Cypionate SCHEMBL6151889 | 1.00 | CYP3A4 (0.76) | CYP3A4LMNATSHRMAPTPGR | |
| Testosterone Cypionate SCHEMBL1170689 | 1.00 | CYP3A4 (0.76) | CYP3A4LMNATSHRMAPTPGR | |
| Testosterone Cypionate SCHEMBL40862 | 1.00 | CYP3A4 (0.76) | CYP3A4LMNATSHRMAPTPGR | |
| Testosterone Cypionate SCHEMBL18078434 | 1.00 | CYP3A4 (0.76) | CYP3A4LMNATSHRMAPTPGR | |
| Testosterone Cypionate SCHEMBL26224948 | 1.00 | CYP3A4 (0.76) | CYP3A4LMNATSHRMAPTPGR | |
| Testosterone Cypionate SCHEMBL5021654 | 1.00 | CYP3A4 (0.76) | CYP3A4LMNATSHRMAPTPGR | |
| Testosterone Cypionate SCHEMBL12754434 | 1.00 | CYP3A4 (0.76) | CYP3A4LMNATSHRMAPTPGR | |
| Testosterone Cypionate SCHEMBL10432170 | 0.99 | CYP3A4 (0.75) | CYP3A4LMNATSHRMAPTPGR | |
| Testosterone Cypionate SCHEMBL5697113 | 0.99 | CYP3A4 (0.75) | CYP3A4LMNATSHRMAPTPGR | |
| SCHEMBL5664755 | 0.99 | CYP3A4 (0.75) | CYP3A4LMNATSHRMAPTPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160287608-A1 | Methods for Inhibiting the Development of Huntington's Disease | CARNAZZA JAMES A (US) | 2016-10-06 | — | — | US | disclosed |
| US-9389237-B2 | Methods for inhibiting the development of Huntington's disease | CARNAZZA JAMES A (US) | 2016-07-12 | — | — | US | disclosed |
| US-20140329789-A1 | Methods for Inhibiting the Development of Huntington's Disease | CARNAZZA JAMES A (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287608-A1 | Methods for Inhibiting the Development of Huntington's Disease | HTT, HYPK, HSD17B11 | AR 84/4885CYP3A4 4186/4885LMNA 2422/4885 |
| US-20140329789-A1 | Methods for Inhibiting the Development of Huntington's Disease | HTT, HYPK, HSD17B11 | AR 84/4885CYP3A4 4186/4885LMNA 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.