Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16210459 | 0.80 | SSTR4 (0.39) | — | |
| SCHEMBL16210458 | 0.80 | SSTR4 (0.39) | — | |
| SCHEMBL16211556 | 0.79 | MAP3K12 (0.35) | MAP3K12 | |
| SCHEMBL20147254 | 0.72 | — | — | |
| SCHEMBL20586014 | 0.72 | RAB9A (0.38) | MAP3K12 | |
| SCHEMBL20586012 | 0.72 | RAB9A (0.38) | MAP3K12 | |
| SCHEMBL20586011 | 0.72 | RAB9A (0.38) | MAP3K12 | |
| SCHEMBL20587746 | 0.72 | RAB9A (0.38) | MAP3K12 | |
| SCHEMBL16212231 | 0.67 | FFAR1 (0.35) | MAP3K12 | |
| SCHEMBL16211842 | 0.67 | KMT2A (0.37) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991978-A1 | BIHETEROARYL COMPOUNDS AND USES THEREOF | F. Hoffmann-La Roche SA (CH) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177060-A1 | BIHETEROARYL COMPOUNDS AND USES THEREOF | F.HOFFMANN-LA ROCHE AG (CH) | 2014-11-06 | — | — | WO | disclosed |